Urofollitropin
CAS No.: 97048-13-0 (Follicle-stimulating hormone)

Short Description:

Source: Extracted from the urine of menopausal women
Function and use: Stimulate the proliferation and differentiation of granulosa cells, induce the synthesis of granulosa cell receptors, and bind to the receptors, activate the activity of enzymes in the body, promote the transformation between hormones, regulate the growth and development of human organs, sexual maturation and reproductive activities A series of related physiological processes. Regulates the menstrual cycle of women to promote follicular development and ovulation in women, regulates testicular function and gonadotropin secretion in men, and treats male infertility; it is clinically used for in vitro reproductive assistance.

Urofollitropin-Pharmacopoeia Standard: BP/EP


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Indications

1. It is mainly used in combination with chorionic gonadotropin for anovulatory infertility caused by insufficient gonadotropin secretion (hypothalamic pituitary dysfunction or disharmony). It is generally recommended to be used in cases of ineffective ovulation induction such as clomiphene (CC) or bromocriptine.

2. Combined with chorionic gonadotropin, it is used for the treatment of primary or secondary amenorrhea and ovarian function test.

3. It is used for polycystic ovary syndrome (PCOS), especially for those who are ineffective with clomiphene.

4. In the assisted pregnancy technology, the stimulation of superovulation in normal ovulating women is often used in combination with clomiphene and chorionic gonadotropin to obtain multiple eggs at a time.

5. Combined with chorionic gonadotropin to treat male hypogonadism and infertility, and stimulate spermatogenic function.


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